Early revisits to the emergency department before and after a protocol for adult asthma exacerbations: a retrospective cohort study

Authors

Abstract

Objective: To compare revisits to the emergency department (ED) for asthma during the week following discharge and describe associated factors before and after the implementation of an assistance protocol.

Materials y methods: A retrospective cohort study was conducted, including visits for asthma exacerbations in adults to the ED of a university hospital during the periods 2016-2018 (pre-protocol) and 2019-2020 (post-protocol). A multivariate logistic regression model was used, and the odds ratios (OR) with their 95% confidence intervals (95 % CI) were reported. A p-value < 0.05 was considered significant.

Results: Revisits were 38 (31.40%) for the pre-protocol period and 33 (26.61%) for the post-protocol period. In the multivariate regression model, no differences were found in early revisits when comparing the post-protocol period with the pre-protocol period (OR 0.68; 95 % CI: 0.26-1.74; p=0.421). Factors associated with early revisits were age (OR: 1.02; 95 % CI:1.00-1.04; p=0.017), male sex (OR: 0.21; 95 % CI:0.08-0.59: p=0.003), and having had more than one visit to the ED in the last year (OR: 6.19; 95 % CI: 2.48-15.46; p<0.001).

Conclusion: Although early revisits did not decrease after the protocol implementation, age and having had more than one visit to the ED for asthma in the last year were identified as risk factors for revisits within the week, while male sex was a protective factor.

References

Mauer Y, Taliercio RM. Managing adult asthma: The 2019 GINA guidelines. Cleve Clin J Med. 2020 Aug 31;87(9):569–75. doi: https://doi.org/10.3949/ccjm.87a.19136
Crossref | Google Scholar

Arias SJ, Neffen H, Bossio JC, Calabrese CA, Videla AJ, Armando GA, et al. Prevalence and Features of Asthma in Young Adults in Urban Areas of Argentina. Arch Bronconeumol. 2018 Mar;54(3):134–9. doi: https://doi.org/10.1016/j.arbr.2018.01.014
Crossref | Google Scholar

Parisi CAS, Zunino S, Las Heras M, Orazi L, Bustamante L, Juszkiewicz E, et al. [The epidemiology of asthma in adults. An insight]. Rev Alerg Mex. 2020 Oct;67(4):397–400. doi: https://doi.org/10.29262/ram.v67i4.816
Crossref | Google Scholar

Neffen H, Gonzalez SN, Fritscher CC, Dovali C, Williams AE. The burden of unscheduled health care for asthma in Latin America. J Investig Allergol Clin Immunol. 2010;20(7):596-601.

Neffen H, Fritscher C, Schacht FC, Levy G, Chiarella P, Soriano JB, et al. Asthma control in Latin America: the Asthma Insights and Reality in Latin America (AIRLA) survey. Rev Panam Salud Publica. 2005 Mar;17(3):191–7. doi: https://doi.org/10.1590/S1020-49892005000300007
Crossref | Google Scholar

Johnson LH, Chambers P, Dexheimer JW. Asthma-related emergency department use: current perspectives. Open Access Emerg Med. 2016 Jul 13;8:47–55. doi: https://doi.org/10.2147/OAEM.S69973
Crossref | Google Scholar

Giunta DH, Marquez Fosser S, Boietti BR, Ación L, Pollan JA, Martínez B, Luna D, Bonella MB, Grande Ratti MF. Emergency department visits and hospital readmissions in an Argentine health system. Int J Med Inform. 2020 Sep;141:104236. doi: https://doi.org/10.1016/j.ijmedinf.2020.104236
Crossref | Google Scholar

Sah R, Murmu LR, Aggarwal P, Bhoi S. Characteristics of an Unscheduled Emergency Department Revisit Within 72 hours of Discharge. Cureus. 2022 Apr;14(4):e23975. doi: https://doi.org/10.7759/cureus.23975
Crossref | Google Scholar

Bhogal SK, McGillivray D, Bourbeau J, Benedetti A, Bartlett S, Ducharme FM. Early administration of systemic corticosteroids reduces hospital admission rates for children with moderate and severe asthma exacerbation. Ann Emerg Med. 2012 Jul;60(1):84–91.e3. doi: https://doi.org/10.1016/j.annemergmed.2011.12.027
Crossref | Google Scholar

Zemek R, Plint A, Osmond MH, Kovesi T, Correll R, Perri N, et al. Triage nurse initiation of corticosteroids in pediatric asthma is associated with improved emergency department efficiency. Pediatrics. 2012 Apr;129(4):671–80. doi: https://doi.org/10.1542/peds.2011-2347
Crossref | Google Scholar

Lougheed MD, Olajos-Clow J, Szpiro K, Moyse P, Julien B, Wang M, et al. Multicentre evaluation of an emergency department asthma care pathway for adults. CJEM. 2009 May;11(3):215–29. doi: https://doi.org/10.1017/S1481803500011234
Crossref | Google Scholar

Emond SD, Woodruff PG, Lee EY, Singh AK, Camargo CA Jr. Effect of an emergency department asthma program on acute asthma care. Ann Emerg Med. 1999 Sep;34(3):321–5. doi: https://doi.org/10.1016/S0196-0644(99)70125-3
Crossref | Google Scholar

Gogniat E, Fredes S, Tiribelli N, Setten M, Rodrigues La Moglie R, et al. Definición del rol y las competencias del kinesiólogo en la unidad de cuidados intensivos. Rev Arg de Ter Int. [Internet]. 2 de enero de 2019 [citado 4 de mayo de 2024];35(4). Disponible en: https://revista.sati.org.ar/index.php/MI/article/view/592

Moral VP. GEMA4.0. Guía española para el manejo del asma. Archivos de Bronconeumología. [Internet]. Enero 2015. [citado 4 de mayo de 2024];51 (Supl 1):2-54. Disponible en: https://www.archbronconeumol.org/en-linkresolver-gema4-0-guia-espanola-el-manejo-S030028961532812X. doi: https://doi.org/10.1016/S0300-2896(15)32812-X
Crossref | Google Scholar

Guía para el diagnóstico, manejo y tratamiento del asma en pacientes adultos. Banco de Recursos de Comunicación del Ministerio de Salud de la Nación [Internet]. 2020 [citado 4 de mayo de 2024]. Available from: https://bancos.salud.gob.ar/recurso/protocolo-de-orientacion-para-el-diagnostico-y-tratamiento-del-asma-en-adultos

Menga Guillermo, Lombardi Dora, Saez Scherbovsky Pablo, Wustten Carlos Sebastián, Uribe Echavarría Loli, Raimondi Guillermo A et al . Recomendaciones prácticas para el manejo de la crisis asmática en pacientes adultos. Rev. am. med. respir [Internet]. 2015 Dic [citado 4 de mayo de 2024];15( 4 ): 325-335. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-236X2015000400008&lng=es.

Gracia G, Ruiz VR, Martínez B, Grande-Ratti MF, Mayer GF. Efficacy of an educational intervention in the management of an inhalation device among nursing professionals of an emergency department. Enferm Clin (Engl Ed). 2022 Jul-Aug;32(4):279-283. doi: https://doi.org/10.1016/j.enfcle.2022.04.004
Crossref | Google Scholar

[Clasificación Internacional de Enfermedades 10° CIE 10° REVISION] [Internet]. [citado 4 de mayo de 2024]. Disposible en: https://www.sssalud.gob.ar/hospitales/archivos/cie_10_revi.pdf

García-Río F, Calle M, Burgos F, Casan P, Del Campo F, Galdiz JB, et al. Spirometry. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR). Arch Bronconeumol. 2013 Sep;49(9):388–401. doi: https://doi.org/10.1016/j.arbr.2013.07.007
Crossref | Google Scholar

Inoue H, Kozawa M, Milligan KL, Funakubo M, Igarashi A, Loefroth E. A retrospective cohort study evaluating healthcare resource utilization in patients with asthma in Japan. NPJ Prim Care Respir Med. 2019 Apr 29;29(1):13. doi: https://doi.org/10.1038/s41533-019-0128-8
Crossref | Google Scholar

Bond KR, Horsley CA, Williams AB. Non-invasive ventilation use in status asthmaticus: 16 years of experience in a tertiary intensive care. Emerg Med Australas. 2018 Apr;30(2):187–92. doi: https://doi.org/10.1111/1742-6723.12876
Crossref | Google Scholar

Rowe BH, Voaklander DC, Wang D, Senthilselvan A, Klassen TP, Marrie TJ, et al. Asthma presentations by adults to emergency departments in Alberta, Canada: a large population-based study. Chest. 2009 Jan;135(1):57–65. doi: https://doi.org/10.1378/chest.07-3041
Crossref | Google Scholar

Haahtela T, Tuomisto LE, Pietinalho A, Klaukka T, Erhola M, Kaila M, et al. A 10 year asthma programme in Finland: major change for the better. Thorax. 2006 Aug;61(8):663–70. doi: https://doi.org/10.1136/thx.2005.055699
Crossref | Google Scholar

Pautas éticas internacionales para la investigación relacionada con la salud con seres humanos [Internet]. 2017 [citado 4 de mayo de 2024]. Available from: https://www.paho.org/es/documentos/pautas-eticas-internacionales-para-investigacion-relacionada-con-salud-con-seres-humanos

Yawn BP, Han MK. Practical Considerations for the Diagnosis and Management of Asthma in Older Adults. Mayo Clin Proc. 2017 Nov;92(11):1697–705. doi: 10.1016/j.mayocp.2017.08.005 doi: https://doi.org/10.1016/j.mayocp.2017.08.005
Crossref | Google Scholar

Busse PJ, McDonald VM, Wisnivesky JP, Gibson PG. Asthma Across the Ages: Adults. J Allergy Clin Immunol Pract. 2020 Jun;8(6):1828–38. doi: https://doi.org/10.1016/j.jaip.2020.03.044
Crossref | Google Scholar

Ali A, Pena SG, Huggins C, Lugo F, Khaja M, Diaz-Fuentes G. Impact of Group Asthma Education on Asthma Control and Emergency Room Visits in an Underserved New York Community. Can Respir J. 2019 Oct 1;2019:5165189. doi: https://doi.org/10.1155/2019/5165189
Crossref | Google Scholar

Walls TA, Hughes NT, Mullan PC, Chamberlain JM, Brown K. Improving Pediatric Asthma Outcomes in a Community Emergency Department. Pediatrics. 2017 Jan;139(1):e20160088. doi: https://doi.org/10.1542/peds.2016-0088
Crossref | Google Scholar

Dexheimer JW, Borycki EM, Chiu KW, Johnson KB, Aronsky D. A systematic review of the implementation and impact of asthma protocols. BMC Med Inform Decis Mak. 2014 Sep 9;14:82. doi: https://doi.org/10.1186/1472-6947-14-82
Crossref | Google Scholar

Aldington S, Beasley R. Asthma exacerbations. 5: assessment and management of severe asthma in adults in hospital. Thorax. 2007 May;62(5):447–58. doi: https://doi.org/10.1136/thx.2005.045203
Crossref | Google Scholar

Rosychuk RJ, Ospina M, Zhang J, Leigh R, Cave A, Rowe BH. Sex differences in outcomes after discharge from Alberta emergency departments for asthma: A large population-based study. J Asthma. 2018 Aug;55(8):817–25. doi: https://doi.org/10.1080/02770903.2017.1373805
Crossref | Google Scholar

Wong AJW, Chan JJ, Koh MS, Lian SWQ, Fook SMC, Ong MEH. Compliance With Asthma Guidelines and Association With Outcomes in the Emergency Department of a Tertiary Care Teaching Hospital. J Acute Med. 2018 Sep 1;8(3):119-126.

Losappio L, Heffler E, Carpentiere R, Fornero M, Cannito CD, Guerrera F, et al. “Characteristics of patients admitted to emergency department for asthma attack: a real-LIFE study.” BMC Pulm Med. 2019 Jun 17;19(1):107. doi: https://doi.org/10.1186/s12890-019-0869-8
Crossref | Google Scholar

McIver M, Stoudemire W, Smith-Ramsey C, Panigrahi M, Walsh-Kelly C, Rutman LE. Improving Timeliness of β-Agonist and Corticosteroid Administration in Patients With Acute Wheezing. Pediatr Emerg Care. 2017 Sep;33(9):635–42. doi: https://doi.org/10.1097/PEC.0000000000001249
Crossref | Google Scholar

Published

2024-06-30

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Ruiz VR, Giunta DH, Zunino SD, Battellini YM, Martinez BJ, Padilla Lopez M, Grande-Ratti MF. Early revisits to the emergency department before and after a protocol for adult asthma exacerbations: a retrospective cohort study. AJRPT. 2024;6(2):40-9. doi: 10.58172/ajrpt.v6i2.311